Protein Modification enzymes play crucial roles in regulating various cellular processes, including protein function, localization,
stability, and interactions. They can alter the activity and function of proteins by modifying specific amino acid residues or by affecting protein-protein interactions.
For example, protein kinases are a type of
Protein Modification Enzyme that catalyze the addition of phosphate groups to specific amino acids, typically serine, threonine, or tyrosine residues. This phosphorylation can activate or deactivate proteins and regulate their interactions with other molecules.
Protein modification enzymes are important for various biological processes, including cell signaling, gene expression, cell cycle regulation, protein degradation, and immune response. Dysregulation of protein modifications can lead to various diseases, including cancer, neurodegenerative disorders, and metabolic disorders.
Studying protein modification enzymes and their substrates is essential for understanding cellular processes and developing therapeutic interventions for diseases.